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Target
Arginase-1
Ligand
BDBM50462601
Substrate
n/a
Meas. Tech.
ChEMBL_1775774 (CHEMBL4232766)
Ki
275000±n/a nM
Citation
 Guo, X; Chen, Y; Seto, CT Rational design of novel irreversible inhibitors for human arginase. Bioorg Med Chem 26:3939-3946 (2018) [PubMed]  Article 
Target
Name:
Arginase-1
Synonyms:
ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
34737.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_978893
Residue:
322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
  
Inhibitor
Name:
BDBM50462601
Synonyms:
CHEMBL4250607
Type:
Small organic molecule
Emp. Form.:
C9H10FN3O2
Mol. Mass.:
211.193
SMILES:
NC(=N)Nc1ccc(cc1)C(F)C(O)=O
Structure:
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