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Target
Lysyl oxidase homolog 4
Ligand
BDBM50463617
Substrate
n/a
Meas. Tech.
ChEMBL_1778830 (CHEMBL4235822)
IC50
55000±n/a nM
Citation
 Hajdú, I; Kardos, J; Major, B; Fabó, G; L?rincz, Z; Cseh, S; Dormán, G Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited. Bioorg Med Chem Lett 28:3113-3118 (2018) [PubMed]  Article 
Target
Name:
Lysyl oxidase homolog 4
Synonyms:
1.4.3.- | LOXC | LOXL4 | LOXL4_HUMAN | Lysyl oxidase homolog 4 | Lysyl oxidase-like protein 4 | Lysyl oxidase-related protein C
Type:
PROTEIN
Mol. Mass.:
84498.74
Organism:
Homo sapiens
Description:
ChEMBL_118171
Residue:
756
Sequence:
MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
  
Inhibitor
Name:
BDBM50463617
Synonyms:
CHEMBL4238380
Type:
Small organic molecule
Emp. Form.:
C18H15N3O2
Mol. Mass.:
305.3306
SMILES:
Cc1cc(c(C)o1)-c1ccc2c(n1)[nH]n(-c1ccccc1)c2=O
Structure:
Search PDB for entries with ligand similarity: