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Target
Melatonin receptor type 1A
Ligand
BDBM50464399
Substrate
n/a
Meas. Tech.
ChEMBL_1780509 (CHEMBL4252026)
EC50
0.900000±n/a nM
Citation
 Duroux, R; Rami, M; Landagaray, E; Ettaoussi, M; Caignard, DH; Delagrange, P; Melnyk, P; Yous, S Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT Eur J Med Chem 141:552-566 (2017) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50464399
Synonyms:
CHEMBL4278446
Type:
Small organic molecule
Emp. Form.:
C18H23N3O2
Mol. Mass.:
313.3941
SMILES:
CCCNC(=O)NCC1CCc2ccc3ccc(OC)nc3c12
Structure:
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