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Target
Transcriptional activator protein LasR
Ligand
BDBM50465708
Substrate
n/a
Meas. Tech.
ChEMBL_1788567 (CHEMBL4260301)
IC50
4030±n/a nM
Citation
 Soukarieh, F; Williams, P; Stocks, MJ; Cámara, M Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives. J Med Chem 61:10385-10402 (2018) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LasR
Synonyms:
LASR_PSEAE | lasR
Type:
PROTEIN
Mol. Mass.:
26618.24
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_1475312
Residue:
239
Sequence:
MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
  
Inhibitor
Name:
BDBM50465708
Synonyms:
CHEMBL3403871
Type:
Small organic molecule
Emp. Form.:
C15H17N5O3
Mol. Mass.:
315.3272
SMILES:
Nc1cccc(c1)-n1cc(CCC(=O)N[C@H]2CCOC2=O)nn1 |r|
Structure:
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