Reaction Details Report a problem with these data
Target
Matrix protein 2
Ligand
BDBM50466338
Substrate
n/a
Meas. Tech.
ChEMBL_1792814 (CHEMBL4264733)
EC50
7730±n/a nM
Citation
 Yu, Y; Tang, Q; Xu, Z; Li, S; Jin, M; Zhao, Z; Dong, C; Wu, S; Zhou, HB Synthesis and structure-activity relationship study of arylsulfonamides as novel potent H5N1 inhibitors. Eur J Med Chem 159:206-216 (2018) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I72A8 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11180.06
Organism:
Influenza A virus (A/Udorn/307/1972(H3N2))
Description:
ChEMBL_22
Residue:
97
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIELE
  
Inhibitor
Name:
BDBM50466338
Synonyms:
CHEMBL4285916
Type:
Small organic molecule
Emp. Form.:
C15H16N2O3S2
Mol. Mass.:
336.429
SMILES:
COc1ccc(cc1)S(=O)(=O)N(CCC#N)Cc1cccs1
Structure:
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