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Target
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Ligand
BDBM50026232
Substrate
n/a
Meas. Tech.
ChEBML_159843
Ki
300±n/a nM
Citation
 Bey, P; Bolkenius, FN; Seiler, N; Casara, P N-2,3-Butadienyl-1,4-butanediamine derivatives: potent irreversible inactivators of mammalian polyamine oxidase. J Med Chem 28:1-2 (1985) [PubMed]  Article 
Target
Name:
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
Synonyms:
Acetylpolyamine oxidase (APAO) | PAO | PAOX | PAOX_HUMAN | Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Polyamine oxidase
Type:
Enzyme
Mol. Mass.:
70274.33
Organism:
Homo sapiens (Human)
Description:
Q6QHF9
Residue:
511
Sequence:
MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL
  
Inhibitor
Name:
BDBM50026232
Synonyms:
CHEMBL293698 | N-Buta-2,3-dienyl-N'-methyl-butane-1,4-diamine
Type:
Small organic molecule
Emp. Form.:
C9H18N2
Mol. Mass.:
154.2526
SMILES:
CNCCCCNCC=C=C
Structure:
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