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Target
Beta-galactosidase
Ligand
BDBM50468277
Substrate
n/a
Meas. Tech.
ChEMBL_1799226 (CHEMBL4271518)
Ki
58000±n/a nM
Citation
 Carmona, AT; Carrión-Jiménez, S; Pingitore, V; Moreno-Clavijo, E; Robina, I; Moreno-Vargas, AJ Harnessing pyrrolidine iminosugars into dimeric structures for the rapid discovery of divalent glycosidase inhibitors. Eur J Med Chem 151:765-776 (2018) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
β-galactosidase | BGAL_BOVIN | Beta-galactosidase/Glucosylceramidase | GLB1
Type:
Protein
Mol. Mass.:
73420.88
Organism:
Bos taurus (Bovine)
Description:
n/a
Residue:
653
Sequence:
MPGVVRLLALLLVPLLLGSARGLHNATQRTFQIDYRRNRFLKDGQPFRYISGSIHYFRVPRFYWKDRLLKMKMAGLNAIQTYVAWNFHELQPGRYNFSGDHDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKKSIVLRSSDPDYLAAVDKWLGVLLPKMRPLLYKNGGPIITVQVENEYGSYLSCDYDYLRFLQKRFHDHLGEDVLLFTTDGVNERLLQCGALQGLYATVDFSPGTNLTAAFMLQRKFEPTGPLVNSEFYTGWLDHWGQRHSTVSSKAVAFTLHDMLALGANVNMYMFIGGTNFAYWNGANIPYQPQPTSYDYDAPLSEAGDLTEKYFALRDIIQKFAKVPEGPIPPSTPKFAYGKVALNKLKTVEDALNILCPSGPIKSVYPLTFIDVKQYFGFVLYRTMLPEDCSDPTPLSSPLSGVHDRAYVSVNGVAQGILERESVITLNITGKAGATLDLLVENMGRVNYGSSINDFKGLVSNLTLGSKILTNWEIFPLDMEDAVRSHLGTWGGRDRGYHNKARAHSPPTYALPTFYVGNFTIPSGIADLPQDTFIQFPGWTKGQVWINGFNLGRYWPVRGPQMTLFVPQHILVTSTPNTIVVLELEHAPCQDGGPELCTVEFVDKPVFRTVQTHRHAN
  
Inhibitor
Name:
BDBM50468277
Synonyms:
CHEMBL4288198
Type:
Small organic molecule
Emp. Form.:
C19H29N5O4
Mol. Mass.:
391.4647
SMILES:
CCCCCCn1cc(CNC(=O)c2cc(oc2C)[C@H]2NC[C@@H](O)[C@H]2O)nn1 |r|
Structure:
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