Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50468336
Substrate
n/a
Meas. Tech.
ChEMBL_1799358 (CHEMBL4271650)
EC50
3.2±n/a nM
Citation
 Ge, X; Woo, AY; Xing, G; Lu, Y; Mo, Y; Zhao, Y; Lan, Y; Li, J; Yan, H; Pan, L; Zhang, Y; Lin, B; Cheng, M Synthesis and biological evaluation of ? Eur J Med Chem 152:424-435 (2018) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50468336
Synonyms:
CHEMBL4283676
Type:
Small organic molecule
Emp. Form.:
C19H20N2O4
Mol. Mass.:
340.3731
SMILES:
OCC(NCCc1ccc(O)cc1)c1ccc(O)c2[nH]c(=O)ccc12
Structure:
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