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Target
Tartrate-resistant acid phosphatase type 5
Ligand
BDBM50469088
Substrate
n/a
Meas. Tech.
ChEMBL_1802620 (CHEMBL4274912)
Ki
120000±n/a nM
Citation
 Hussein, WM; Feder, D; Schenk, G; Guddat, LW; McGeary, RP Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics. Eur J Med Chem 157:462-479 (2018) [PubMed]  Article 
Target
Name:
Tartrate-resistant acid phosphatase type 5
Synonyms:
3.1.3.2 | ACP5 | PPA5_PIG | TR-AP | Tartrate-resistant acid ATPase | Tartrate-resistant acid phosphatase type 5 | TrATPase | Type 5 acid phosphatase | Uteroferrin
Type:
PROTEIN
Mol. Mass.:
38029.68
Organism:
Sus scrofa
Description:
ChEMBL_117953
Residue:
340
Sequence:
MDTWTVLLILQASLVLPGAVGTRTNTRTAPTPILRFVAVGDWGGVPNAPFHTAREMANAKAIATTVKTLGADFILSLGDNFYFTGVHDAKDKRFQETFEDVFSDPSLRNVPWHVLAGNHDHLGNVSAQIAYSKISKRWNFPSPYYRLRFKIPRSNVSVAIFMLDTVTLCGNSDDFVSQQPERPRNLALARTQLAWIKKQLAAAKEDYVLVAGHYPVWSIAEHGPTHCLVKQLLPLLTTHKVTAYLCGHDHNLQYLQDENGLGFVLSGAGNFMDPSKKHLRKVPNGYLRFHFGAENSLGGFAYVEITPKEMSVTYIEASGKSLFKTKLPRRARSEHQHRRA
  
Inhibitor
Name:
BDBM50469088
Synonyms:
CHEMBL4287988
Type:
Small organic molecule
Emp. Form.:
C11H9NO3S
Mol. Mass.:
235.259
SMILES:
COc1ccc(cc1)-c1nc(cs1)C(O)=O
Structure:
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