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Target
Mu-type opioid receptor
Ligand
BDBM50070386
Substrate
n/a
Meas. Tech.
ChEMBL_1804082 (CHEMBL4276374)
EC50
0.100000±n/a nM
Citation
 Martin, C; Dumitrascuta, M; Mannes, M; Lantero, A; Bucher, D; Walker, K; Van Wanseele, Y; Oyen, E; Hernot, S; Van Eeckhaut, A; Madder, A; Hoogenboom, R; Spetea, M; Ballet, S Biodegradable Amphipathic Peptide Hydrogels as Extended-Release System for Opioid Peptides. J Med Chem 61:9784-9789 (2018) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50070386
Synonyms:
CHEMBL3408737
Type:
Small organic molecule
Emp. Form.:
C30H42N8O5
Mol. Mass.:
594.7051
SMILES:
[H][C@@]1(Cc2ccccc2CN(CCC(N)=O)C1=O)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C |r|
Structure:
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