Target
Thymidine kinase
Ligand
BDBM50472274
Substrate
n/a
Meas. Tech.
ChEMBL_80696 (CHEMBL690791)
EC50
>3750±n/a nM
Citation
 Holý, AGünter, JDvoráková, HMasojídková, MAndrei, GSnoeck, RBalzarini, JDe Clercq, E Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base. J Med Chem 42:2064-86 (1999) [PubMed]  Article 
Target
Name:
Thymidine kinase
Synonyms:
2.7.1.21 | HHV3M2gp38 | HHV3_gp38 | HHV3gp38 | ORF36 | TK | Thymidine kinase
Type:
PROTEIN
Mol. Mass.:
37846.07
Organism:
Human herpesvirus 3
Description:
ChEMBL_14068
Residue:
341
Sequence:
MSTDKTDVKMGVLRIYLDGAYGIGKTTAAEEFLHHFAITPNRILLIGEPLSYWRNLAGEDAICGIYGTQTRRLNGDVSPEDAQRLTAHFQSLFCSPHAIMHAKISALMDTSTSDLVQVNKEPYKIMLSDRHPIASTICFPLSRYLVGDMSPAALPGLLFTLPAEPPGTNLVVCTVSLPSHLSRVSKRARPGETVNLPFVMVLRNVYIMLINTIIFLKTNNWHAGWNTLSFCNDVFKQKLQKSECIKLREVPGIEDTLFAVLKLPELCGEFGNILPLWAWGMETLSNCLRSMSPFVLSLEQTPQHAAQELKTLLPQMTPANMSSGAWNILKELVNAVQDNTS
  
Inhibitor
Name:
BDBM50472274
Synonyms:
CHEMBL62595
Type:
Small organic molecule
Emp. Form.:
C24H43ClN5O4P
Mol. Mass.:
532.056
SMILES:
CC(C)CCCCCOP(=O)(COCCn1cnc2c(Cl)nc(N)nc12)OCCCCCC(C)C
Structure:
Search PDB for entries with ligand similarity: