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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM10890
Substrate
n/a
Meas. Tech.
ChEMBL_211347 (CHEMBL815040)
IC50
>100000±n/a nM
Citation
 Owa, T; Yokoi, A; Yamazaki, K; Yoshimatsu, K; Yamori, T; Nagasu, T Array-based structure and gene expression relationship study of antitumor sulfonamides including N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide and N-(3-chloro-7-indolyl)-1,4-benzenedisulfonamide. J Med Chem 45:4913-22 (2002) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM10890
Synonyms:
1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide | CHEMBL77517 | Compound 6 | E7070 | Indisulam (IND) | Sulfonamide, 7
Type:
Small organic molecule
Emp. Form.:
C14H12ClN3O4S2
Mol. Mass.:
385.846
SMILES:
NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12
Structure:
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