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Target
ATP-dependent RNA helicase SUPV3L1, mitochondrial
Ligand
BDBM50474373
Substrate
n/a
Meas. Tech.
ChEMBL_206610 (CHEMBL810795)
IC50
>1290000±n/a nM
Citation
 Zhang, N; Chen, HM; Koch, V; Schmitz, H; Minczuk, M; Stepien, P; Fattom, AI; Naso, RB; Kalicharran, K; Borowski, P; Hosmane, RS Potent inhibition of NTPase/helicase of the West Nile Virus by ring-expanded ("fat") nucleoside analogues. J Med Chem 46:4776-89 (2003) [PubMed]  Article 
Target
Name:
ATP-dependent RNA helicase SUPV3L1, mitochondrial
Synonyms:
3.6.4.13 | ATP-dependent RNA helicase SUPV3L1, mitochondrial | SUPV3L1 | SUV3 | SUV3-like protein 1 | SUV3_HUMAN | Suppressor of var1 3-like protein 1
Type:
PROTEIN
Mol. Mass.:
88005.34
Organism:
Homo sapiens
Description:
ChEMBL_18003
Residue:
786
Sequence:
MSFSRALLWARLPAGRQAGHRAAICSALRPHFGPFPGVLGQVSVLATASSSASGGSKIPNTSLFVPLTVKPQGPSADGDVGAELTRPLDKNEVKKVLDKFYKRKEIQKLGADYGLDARLFHQAFISFRNYIMQSHSLDVDIHIVLNDICFGAAHADDLFPFFLRHAKQIFPVLDCKDDLRKISDLRIPPNWYPDARAMQRKIIFHSGPTNSGKTYHAIQKYFSAKSGVYCGPLKLLAHEIFEKSNAAGVPCDLVTGEERVTVQPNGKQASHVSCTVEMCSVTTPYEVAVIDEIQMIRDPARGWAWTRALLGLCAEEVHLCGEPAAIDLVMELMYTTGEEVEVRDYKRLTPISVLDHALESLDNLRPGDCIVCFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQAKKFNDPNDPCKILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRFKEGEVTTMNHEDLSLLKEILKRPVDPIRAAGLHPTAEQIEMFAYHLPDATLSNLIDIFVDFSQVDGQYFVCNMDDFKFSAELIQHIPLSLRVRYVFCTAPINKKQPFVCSSLLQFARQYSRNEPLTFAWLRRYIKWPLLPPKNIKDLMDLEAVHDVLDLYLWLSYRFMDMFPDASLIRDLQKELDGIIQDGVHNITKLIKMSETHKLLNLEGFPSGSQSRLSGTLKSQARRTRGTKALGSKATEPPSPDAGELSLASRLVQQGLLTPDMLKQLEKEWMTQQTEHNKEKTESGTHPKGTRRKKKEPDSD
  
Inhibitor
Name:
BDBM50474373
Synonyms:
CHEMBL611608
Type:
Small organic molecule
Emp. Form.:
C17H17N5O6
Mol. Mass.:
387.3468
SMILES:
OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c1c(=O)[nH]c(Nc1ccccc1)nc2=O |r|
Structure:
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