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Target
Sphingosine 1-phosphate receptor 4
Ligand
BDBM50475576
Substrate
n/a
Meas. Tech.
ChEMBL_328366 (CHEMBL864565)
EC50
1.3±n/a nM
Citation
 Ettmayer, P; Baumruker, T; Guerini, D; Mechtcheriakova, D; Nussbaumer, P; Streiff, MB; Billich, A NBD-labeled derivatives of the immunomodulatory drug FTY720 as tools for metabolism and mode of action studies. Bioorg Med Chem Lett 16:84-7 (2006) [PubMed]  Article 
Target
Name:
Sphingosine 1-phosphate receptor 4
Synonyms:
EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41647.39
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI
  
Inhibitor
Name:
BDBM50475576
Synonyms:
CHEMBL199791
Type:
Small organic molecule
Emp. Form.:
C15H32NO5P
Mol. Mass.:
337.392
SMILES:
CCCCCCCCCC\C=C\[C@@H](O)[C@@H](N)COP(O)(O)=O
Structure:
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