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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50385682
Substrate
n/a
Meas. Tech.
ChEMBL_432434 (CHEMBL917429)
EC50
37100±n/a nM
Citation
 Piergentili, A; Quaglia, W; Giannella, M; Del Bello, F; Bruni, B; Buccioni, M; Carrieri, A; Ciattini, S Dioxane and oxathiane nuclei: suitable substructures for muscarinic agonists. Bioorg Med Chem 15:886-96 (2007) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2
Type:
GPCR
Mol. Mass.:
51730.61
Organism:
Homo sapiens (Human)
Description:
P08172
Residue:
466
Sequence:
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50385682
Synonyms:
CHEMBL390842
Type:
Small organic molecule
Emp. Form.:
C9H20NO2
Mol. Mass.:
174.2601
SMILES:
C[C@H]1COC[C@@H](C[N+](C)(C)C)O1 |r|
Structure:
Search PDB for entries with ligand similarity: