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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50003014
Substrate
n/a
Meas. Tech.
ChEMBL_432433 (CHEMBL917428)
EC50
38900±n/a nM
Citation
 Piergentili, A; Quaglia, W; Giannella, M; Del Bello, F; Bruni, B; Buccioni, M; Carrieri, A; Ciattini, S Dioxane and oxathiane nuclei: suitable substructures for muscarinic agonists. Bioorg Med Chem 15:886-96 (2007) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1
Type:
Protein
Mol. Mass.:
51442.54
Organism:
Homo sapiens (Human)
Description:
P11229
Residue:
460
Sequence:
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50003014
Synonyms:
CHEMBL228144
Type:
Small organic molecule
Emp. Form.:
C9H20INO2
Mol. Mass.:
301.1651
SMILES:
[I-].CC1COCC(C[N+](C)(C)C)O1
Structure:
Search PDB for entries with ligand similarity: