Reaction Details Report a problem with these data
Target
Protein Tat
Ligand
BDBM50476285
Substrate
n/a
Meas. Tech.
ChEMBL_434784 (CHEMBL917012)
EC50
1000±n/a nM
Citation
 Pan, C; Mezei, M; Mujtaba, S; Muller, M; Zeng, L; Li, J; Wang, Z; Zhou, MM Structure-guided optimization of small molecules inhibiting human immunodeficiency virus 1 Tat association with the human coactivator p300/CREB binding protein-associated factor. J Med Chem 50:2285-8 (2007) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | TAT_HV1H2 | tat
Type:
PROTEIN
Mol. Mass.:
9851.32
Organism:
Human immunodeficiency virus type 1 (isolate HXB2 group M subtype B)(HIV-1)
Description:
ChEMBL_320712
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAHQNSQTHQASLSKQPTSQPRGDPTGPKE
  
Inhibitor
Name:
BDBM50476285
Synonyms:
CHEMBL609729
Type:
Small organic molecule
Emp. Form.:
C11H16ClN3O2
Mol. Mass.:
257.717
SMILES:
CC(Cl)c1ccc(NCCCN)c(c1)[N+]([O-])=O
Structure:
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