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Target
Carboxypeptidase A1
Ligand
BDBM50478895
Substrate
n/a
Meas. Tech.
ChEMBL_525570 (CHEMBL969981)
IC50
9.57±n/a nM
Citation
 Murakami, M; Suzuki, S; Itou, Y; Kodani, S; Ishida, K New anabaenopeptins, potent carboxypeptidase-A inhibitors from the cyanobacterium Aphanizomenon flos-aquae. J Nat Prod 63:1280-2 (2000) [PubMed]  Article 
Target
Name:
Carboxypeptidase A1
Synonyms:
CBPA1_HUMAN | CPA | CPA1
Type:
PROTEIN
Mol. Mass.:
47132.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1496378
Residue:
419
Sequence:
MRGLLVLSVLLGAVFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY
  
Inhibitor
Name:
BDBM50478895
Synonyms:
Anabaenopeptin J
Type:
Small organic molecule
Emp. Form.:
C41H59N7O9
Mol. Mass.:
793.9487
SMILES:
CC[C@H](C)[C@H](NC(=O)N[C@@H]1CCCCNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)N(C)C(=O)[C@H](CCc2ccc(O)cc2)NC(=O)[C@@H](NC1=O)C(C)C)C(O)=O |r|
Structure:
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