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Target
Protease
Ligand
BDBM50478910
Substrate
n/a
Meas. Tech.
ChEMBL_491409 (CHEMBL945372)
IC50
107±n/a nM
Citation
 Zhang, M; Nguyen, JT; Kumada, HO; Kimura, T; Cheng, M; Hayashi, Y; Kiso, Y Locking the two ends of tetrapeptidic HTLV-I protease inhibitors inside the enzyme. Bioorg Med Chem 16:6880-90 (2008) [PubMed]  Article 
Target
Name:
Protease
Synonyms:
Protease | prt
Type:
PROTEIN
Mol. Mass.:
13462.60
Organism:
Human T-cell leukemia virus type I
Description:
ChEMBL_118454
Residue:
125
Sequence:
PVIPLDPARRPVIKAQVDTQTSHPKTIEALLDTGADMTVLPIALFSSNTPLKNTSVLGAGGQTQDHFKLTSLPVLIRLPFRTTPIVLTSCLVDTKNNWAIIGRDALQQCQGVLYLPEAKGPPVIL
  
Inhibitor
Name:
BDBM50478910
Synonyms:
CHEMBL500319 | KNI-10667
Type:
Small organic molecule
Emp. Form.:
C40H59N5O6S
Mol. Mass.:
737.991
SMILES:
CC(C)CC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@H](O)C(=O)N1CSC(C)(C)[C@H]1C(=O)NC(C)C(C)C)C(C)(C)C)c1ccccc1 |r|
Structure:
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