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Target
Chymotrypsin-like elastase family member 1/2A
Ligand
BDBM50479191
Substrate
n/a
Meas. Tech.
ChEMBL_510667 (CHEMBL1005628)
IC50
>67000±n/a nM
Citation
 Taori, K; Paul, VJ; Luesch, H Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp. J Nat Prod 71:1625-9 (2008) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 1/2A
Synonyms:
Pancreatic elastase
Type:
n/a
Mol. Mass.:
n/a
Description:
ASSAY_ID of ChEMBL is 152345
Components:
This complex has 2 components.
Component 1
Name:
Chymotrypsin-like elastase family member 1
Synonyms:
Pancreatic elastase | Elastase-1 | Elastase 1 | CELA1_PIG | CELA1 | ELA1 | Elastase
Type:
Enzyme
Mol. Mass.:
28827.71
Organism:
Pig
Description:
P00772
Residue:
266
Sequence:
MLRLLVVASLVLYGHSTQDFPETNARVVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN
  
Component 2
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
Elastase-2 | Elastase-2A | Elastase 2A | CEL2A_PIG | CELA2A | ELA2 | ELA2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Pig
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50479191
Synonyms:
KEMPOPEPTIN B
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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