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Target
Alpha-tocopherol transfer protein
Ligand
BDBM50481301
Substrate
n/a
Meas. Tech.
ChEMBL_605568 (CHEMBL1069214)
Kd
2190±n/a nM
Citation
 López, GV; Gómez, LE; Campillo, N; Páez, JA; Giles, K; Atkinson, J; González, M; Rubbo, H; Cerecetto, H Interaction studies between human alpha-tocopherol transfer protein and nitric oxide donor tocopherol analogues with LDL-protective activity. Bioorg Med Chem 17:8143-8 (2009) [PubMed]  Article 
Target
Name:
Alpha-tocopherol transfer protein
Synonyms:
Alpha-TTP | Alpha-tocopherol transfer protein | TPP1 | TTPA | TTPA_HUMAN
Type:
PROTEIN
Mol. Mass.:
31754.31
Organism:
Homo sapiens
Description:
ChEMBL_109106
Residue:
278
Sequence:
MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
  
Inhibitor
Name:
BDBM50481301
Synonyms:
CHEMBL391747
Type:
Small organic molecule
Emp. Form.:
C25H28N2O9S
Mol. Mass.:
532.563
SMILES:
Cc1c(C)c2OC(C)(CCc2c(C)c1O)C(=O)OCCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1
Structure:
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