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Target
LL-diaminopimelate aminotransferase, chloroplastic
Ligand
BDBM50481543
Substrate
n/a
Meas. Tech.
ChEMBL_613320 (CHEMBL1074257)
IC50
45000±n/a nM
Citation
 Fan, C; Clay, MD; Deyholos, MK; Vederas, JC Exploration of inhibitors for diaminopimelate aminotransferase. Bioorg Med Chem 18:2141-2151 (2010) [PubMed]  Article 
Target
Name:
LL-diaminopimelate aminotransferase, chloroplastic
Synonyms:
2.6.1.83 | AGD2 | AGD2 | AtDAP-AT | DAP | DAP-AT | DAP-aminotransferase | DAPAT_ARATH | LL-DAP-aminotransferase | LL-diaminopimelate aminotransferase, chloroplastic | Protein ABERRANT GROWTH AND DEATH 2
Type:
PROTEIN
Mol. Mass.:
50399.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_109120
Residue:
461
Sequence:
MSSTHQLVSSMISSSSSTFLAPSNFNLRTRNACLPMAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK
  
Inhibitor
Name:
BDBM50481543
Synonyms:
CHEMBL3144829
Type:
Small organic molecule
Emp. Form.:
C17H16N4O4
Mol. Mass.:
340.3333
SMILES:
CN1C(=O)N(C)C(=O)C(=Cc2c(C)[nH]n(-c3ccccc3)c2=O)C1=O |(-4.54,-12.64,;-3.92,-14.05,;-4.82,-15.3,;-6.35,-15.14,;-4.2,-16.7,;-5.1,-17.95,;-2.66,-16.86,;-2.04,-18.27,;-1.76,-15.62,;-.23,-15.78,;.68,-14.53,;2.22,-14.53,;3.12,-15.78,;2.69,-13.07,;1.45,-12.16,;1.45,-10.62,;2.78,-9.85,;2.78,-8.31,;1.45,-7.54,;.11,-8.31,;.11,-9.85,;.2,-13.07,;-1.26,-12.59,;-2.39,-14.21,;-1.91,-12.75,)|
Structure:
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