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Target
LL-diaminopimelate aminotransferase, chloroplastic
Ligand
BDBM50092273
Substrate
n/a
Meas. Tech.
ChEMBL_613320 (CHEMBL1074257)
IC50
>200000±n/a nM
Citation
 Fan, C; Clay, MD; Deyholos, MK; Vederas, JC Exploration of inhibitors for diaminopimelate aminotransferase. Bioorg Med Chem 18:2141-2151 (2010) [PubMed]  Article 
Target
Name:
LL-diaminopimelate aminotransferase, chloroplastic
Synonyms:
2.6.1.83 | AGD2 | AGD2 | AtDAP-AT | DAP | DAP-AT | DAP-aminotransferase | DAPAT_ARATH | LL-DAP-aminotransferase | LL-diaminopimelate aminotransferase, chloroplastic | Protein ABERRANT GROWTH AND DEATH 2
Type:
PROTEIN
Mol. Mass.:
50399.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_109120
Residue:
461
Sequence:
MSSTHQLVSSMISSSSSTFLAPSNFNLRTRNACLPMAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK
  
Inhibitor
Name:
BDBM50092273
Synonyms:
(Z)-5-(2'-Hydroxybenzylidene)-2-thioxothiazolidin-4-one | (Z)-5-(2-Hydroxybenzylidene)-2-thioxothiazolidin-4-one | 5-[1-(2-Hydroxy-phenyl)-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one | CHEMBL431550
Type:
Small organic molecule
Emp. Form.:
C10H7NO2S2
Mol. Mass.:
237.298
SMILES:
Oc1ccccc1C=C1SC(S)=NC1=O |w:7.7,c:12|
Structure:
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