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Target
LL-diaminopimelate aminotransferase, chloroplastic
Ligand
BDBM50241157
Substrate
n/a
Meas. Tech.
ChEMBL_613320 (CHEMBL1074257)
IC50
142000±n/a nM
Citation
 Fan, C; Clay, MD; Deyholos, MK; Vederas, JC Exploration of inhibitors for diaminopimelate aminotransferase. Bioorg Med Chem 18:2141-2151 (2010) [PubMed]  Article 
Target
Name:
LL-diaminopimelate aminotransferase, chloroplastic
Synonyms:
2.6.1.83 | AGD2 | AGD2 | AtDAP-AT | DAP | DAP-AT | DAP-aminotransferase | DAPAT_ARATH | LL-DAP-aminotransferase | LL-diaminopimelate aminotransferase, chloroplastic | Protein ABERRANT GROWTH AND DEATH 2
Type:
PROTEIN
Mol. Mass.:
50399.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_109120
Residue:
461
Sequence:
MSSTHQLVSSMISSSSSTFLAPSNFNLRTRNACLPMAKRVNTCKCVATPQEKIEYKTKVSRNSNMSKLQAGYLFPEIARRRSAHLLKYPDAQVISLGIGDTTEPIPEVITSAMAKKAHELSTIEGYSGYGAEQGAKPLRAAIAKTFYGGLGIGDDDVFVSDGAKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENGFFPDLSTVGRTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVAMETASFSKYAGFTGVRLGWTVIPKKLLYSDGFPVAKDFNRIICTCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTPGSGFGPGGEGFVRVSAFGHRENILEACRRFKQLYK
  
Inhibitor
Name:
BDBM50241157
Synonyms:
(Z)-5-(4'-Methoxybenzylidene)-2-thioxothiazolidin-4-one | (Z)-5-(4-Methoxybenzylidene)-2-thioxothiazolidin-4-one | (Z)-5-(4-methoxlbenzyliden)-2-thioxothiazolidin-4-one | 5-(4-methoxybenzylidene)-2-thioxothiazolidin-4-one | CHEMBL224521
Type:
Small organic molecule
Emp. Form.:
C11H9NO2S2
Mol. Mass.:
251.325
SMILES:
COc1ccc(C=C2SC(S)=NC2=O)cc1 |w:6.5,c:10|
Structure:
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