Reaction Details Report a problem with these data
Target
Matrix protein 2
Ligand
BDBM50216627
Substrate
n/a
Meas. Tech.
ChEMBL_639626 (CHEMBL1175304)
Kd
16±n/a nM
Citation
 Eleftheratos, S; Spearpoint, P; Ortore, G; Kolocouris, A; Martinelli, A; Martin, S; Hay, A Interaction of aminoadamantane derivatives with the influenza A virus M2 channel-docking using a pore blocking model. Bioorg Med Chem Lett 20:4182-7 (2010) [PubMed]  Article 
Target
Name:
Matrix protein 2
Synonyms:
M | M2_I000F | Matrix protein 2 | Proton channel protein M2
Type:
PROTEIN
Mol. Mass.:
11173.62
Organism:
Influenza A virus
Description:
ChEMBL_117202
Residue:
97
Sequence:
MSLLTEVETPTRNGWECSCSDSSDPLVIAASIIGILHFILWILDRLFFKCIYRRLKYGLKRGPSTEGVPKSMREEYRQEQQNAVDVDDGHFVNIELE
  
Inhibitor
Name:
BDBM50216627
Synonyms:
(alpha-methyl-1-adamantyl)methylamine | 1-Adamantan-1-yl-ethylamine | CHEMBL959 | RIMANTADINE | US11241393, Rimantadine | rimantadin | rimantidin
Type:
Small organic molecule
Emp. Form.:
C12H21N
Mol. Mass.:
179.3018
SMILES:
CC(N)C12CC3CC(CC(C3)C1)C2 |TLB:10:5:12:9.8.11,10:9:12:6.5.4,THB:4:5:8:12.3.11,4:3:6.5.10:8,1:3:6.5.10:8|
Structure:
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