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Target
General amino-acid permease GAP1
Ligand
BDBM50407456
Substrate
n/a
Meas. Tech.
ChEMBL_650859 (CHEMBL1228074)
Ki
190000±n/a nM
Citation
 Van Zeebroeck, G; Bonini, BM; Versele, M; Thevelein, JM Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nat Chem Biol 5:45-52 (2009) [PubMed]  Article 
Target
Name:
General amino-acid permease GAP1
Synonyms:
GAP1 | GAP1_YEAST | General amino-acid permease GAP1
Type:
PROTEIN
Mol. Mass.:
65663.80
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_109239
Residue:
602
Sequence:
MSNTSSYEKNNPDNLKHNGITIDSEFLTQEPITIPSNGSAVSIDETGSGSKWQDFKDSFKRVKPIEVDPNLSEAEKVAIITAQTPLKHHLKNRHLQMIAIGGAIGTGLLVGSGTALRTGGPASLLIGWGSTGTMIYAMVMALGELAVIFPISGGFTTYATRFIDESFGYANNFNYMLQWLVVLPLEIVSASITVNFWGTDPKYRDGFVALFWLAIVIINMFGVKGYGEAEFVFSFIKVITVVGFIILGIILNCGGGPTGGYIGGKYWHDPGAFAGDTPGAKFKGVCSVFVTAAFSFAGSELVGLAASESVEPRKSVPKAAKQVFWRITLFYILSLLMIGLLVPYNDKSLIGASSVDAAASPFVIAIKTHGIKGLPSVVNVVILIAVLSVGNSAIYACSRTMVALAEQRFLPEIFSYVDRKGRPLVGIAVTSAFGLIAFVAASKKEGEVFNWLLALSGLSSLFTWGGICICHIRFRKALAAQGRGLDELSFKSPTGVWGSYWGLFMVIIMFIAQFYVAVFPVGDSPSAEGFFEAYLSFPLVMVMYIGHKIYKRNWKLFIPAEKMDIDTGRREVDLDLLKQEIAEEKAIMATKPRWYRIWNFWC
  
Inhibitor
Name:
BDBM50407456
Synonyms:
CHEMBL55711
Type:
Small organic molecule
Emp. Form.:
C8H16N2O3
Mol. Mass.:
188.2242
SMILES:
CC(C)C[C@H](N)C(=O)NCC(O)=O
Structure:
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