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Target
Alpha-1,2-mannosidase, putative
Ligand
BDBM50482721
Substrate
n/a
Meas. Tech.
ChEMBL_662778 (CHEMBL1252517)
Ki
230000±n/a nM
Citation
 Zhu, Y; Suits, MD; Thompson, AJ; Chavan, S; Dinev, Z; Dumon, C; Smith, N; Moremen, KW; Xiang, Y; Siriwardena, A; Williams, SJ; Gilbert, HJ; Davies, GJ Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont. Nat Chem Biol 6:125-32 (2010) [PubMed]  Article 
Target
Name:
Alpha-1,2-mannosidase, putative
Synonyms:
Alpha-1,2-mannosidase, putative
Type:
PROTEIN
Mol. Mass.:
87740.67
Organism:
Bacteroides thetaiotaomicron
Description:
ChEMBL_117209
Residue:
782
Sequence:
MYKASANILIACSFLWLTACSSAGVVTEDLIPTDYVNPFIGASTSVGAAGVYHGLGKTFPGATTPYGMVQVSPNTITGGDNSSGYSDEHKTIEGFAFTQMSGVGWFGDLGNFLVMPTTGELQKIAGKEDGSIKGYRSSYDKATETAKAGYYSVELTDYKIKVESSATPHCGILQFTFPSNEQSRIQIDLARRVGGTSTSQYVKVLDDYTIQGWMKCTPDGGGWGNGEGNSDYTVYYYAQFSKPLSNYGFWSADIPDEWVRKRDEVVSIPYLTRISQAPVIKDKKELEGKHLGFFTEFPTKEGEQVEMKVGISFVDMEGAANNFKQEIASKNFAQVKQEASDLWNKELSRIRISGGTDDEKTVFYTSLYHTMIDPRIYTDVDGRYIGGDKKVHEQDGTFTKRTIFSGWDVFRSQFPLQAMINPRLVSDALNSLITMADQSRREYYERWELLNSYSGCMIGNPALSVLADAYMKGIRTYDVEKAYQYAVNTSAKFGNDSLGYTPEPLSISYTLEYAYADWCVAQLAKALGKEEDAKRFYEKGQAYRNMFDAEKGWFRPRNADGSWKAWPENALTEEWYGCIESNAYQQGWFVPHDVPGMVELMGGKEEVIANLTNLFDHTPSDMLWNDYYNHANEPVHFVPFLFNQLDVPWYTQKWTRYICKNAYANKVEGIVGNEDVGQMSAWYILAASGIHPSCPGNTRMEITSPVFDKVEFNLDSKYHQGKVFTIIAHNNNTNNLYIQKALLNGKEYNKCYLDFAEIAAGGTLELFMGDKPNTEWGVLSNI
  
Inhibitor
Name:
BDBM50482721
Synonyms:
Kifunensine
Type:
Small organic molecule
Emp. Form.:
C8H12N2O6
Mol. Mass.:
232.1907
SMILES:
[H][C@]12NC(=O)C(=O)N1[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O |r|
Structure:
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