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Target
Alpha-1,2-mannosidase, putative
Ligand
BDBM36373
Substrate
n/a
Meas. Tech.
ChEMBL_662789 (CHEMBL1252528)
Ki
360000±n/a nM
Citation
 Zhu, Y; Suits, MD; Thompson, AJ; Chavan, S; Dinev, Z; Dumon, C; Smith, N; Moremen, KW; Xiang, Y; Siriwardena, A; Williams, SJ; Gilbert, HJ; Davies, GJ Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont. Nat Chem Biol 6:125-32 (2010) [PubMed]  Article 
Target
Name:
Alpha-1,2-mannosidase, putative
Synonyms:
Alpha-1,2-mannosidase, putative
Type:
PROTEIN
Mol. Mass.:
87740.67
Organism:
Bacteroides thetaiotaomicron
Description:
ChEMBL_117209
Residue:
782
Sequence:
MYKASANILIACSFLWLTACSSAGVVTEDLIPTDYVNPFIGASTSVGAAGVYHGLGKTFPGATTPYGMVQVSPNTITGGDNSSGYSDEHKTIEGFAFTQMSGVGWFGDLGNFLVMPTTGELQKIAGKEDGSIKGYRSSYDKATETAKAGYYSVELTDYKIKVESSATPHCGILQFTFPSNEQSRIQIDLARRVGGTSTSQYVKVLDDYTIQGWMKCTPDGGGWGNGEGNSDYTVYYYAQFSKPLSNYGFWSADIPDEWVRKRDEVVSIPYLTRISQAPVIKDKKELEGKHLGFFTEFPTKEGEQVEMKVGISFVDMEGAANNFKQEIASKNFAQVKQEASDLWNKELSRIRISGGTDDEKTVFYTSLYHTMIDPRIYTDVDGRYIGGDKKVHEQDGTFTKRTIFSGWDVFRSQFPLQAMINPRLVSDALNSLITMADQSRREYYERWELLNSYSGCMIGNPALSVLADAYMKGIRTYDVEKAYQYAVNTSAKFGNDSLGYTPEPLSISYTLEYAYADWCVAQLAKALGKEEDAKRFYEKGQAYRNMFDAEKGWFRPRNADGSWKAWPENALTEEWYGCIESNAYQQGWFVPHDVPGMVELMGGKEEVIANLTNLFDHTPSDMLWNDYYNHANEPVHFVPFLFNQLDVPWYTQKWTRYICKNAYANKVEGIVGNEDVGQMSAWYILAASGIHPSCPGNTRMEITSPVFDKVEFNLDSKYHQGKVFTIIAHNNNTNNLYIQKALLNGKEYNKCYLDFAEIAAGGTLELFMGDKPNTEWGVLSNI
  
Inhibitor
Name:
BDBM36373
Synonyms:
(5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-6,7,8-triol. 1a | CID10013016
Type:
Small organic molecule
Emp. Form.:
C8H12N2O4
Mol. Mass.:
200.1919
SMILES:
OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12
Structure:
Search PDB for entries with ligand similarity: