Reaction Details Report a problem with these data
Target
Histamine H2 receptor
Ligand
BDBM22880
Substrate
n/a
Meas. Tech.
ChEMBL_697511 (CHEMBL1638843)
EC50
3162±n/a nM
Citation
 Igel, P; Dove, S; Buschauer, A Histamine H4 receptor agonists. Bioorg Med Chem Lett 20:7191-9 (2010) [PubMed]  Article 
Target
Name:
Histamine H2 receptor
Synonyms:
Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_HUMAN | Histamine H2 receptor | Histamine H2-Gs alpha S
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40115.31
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
359
Sequence:
MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR
  
Inhibitor
Name:
BDBM22880
Synonyms:
2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine | 4-Methylhistamine | Methylhistamine-4
Type:
Small organic molecule
Emp. Form.:
C6H11N3
Mol. Mass.:
125.1716
SMILES:
Cc1nc[nH]c1CCN
Structure:
Search PDB for entries with ligand similarity: