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Target
Tubulin beta chain
Ligand
BDBM50483308
Substrate
n/a
Meas. Tech.
ChEMBL_700038 (CHEMBL1646630)
Kd
17900±n/a nM
Citation
 Yamazaki, Y; Kido, Y; Hidaka, K; Yasui, H; Kiso, Y; Yakushiji, F; Hayashi, Y Tubulin photoaffinity labeling study with a plinabulin chemical probe possessing a biotin tag at the oxazole. Bioorg Med Chem 19:595-602 (2011) [PubMed]  Article 
Target
Name:
Tubulin beta chain
Synonyms:
Beta-tubulin | TBB_PIG | Tubulin beta chain
Type:
PROTEIN
Mol. Mass.:
49840.26
Organism:
Sus scrofa
Description:
ChEMBL_105107
Residue:
445
Sequence:
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEGEEDEA
  
Inhibitor
Name:
BDBM50483308
Synonyms:
CHEMBL1643852
Type:
Small organic molecule
Emp. Form.:
C53H67N11O8S
Mol. Mass.:
1018.233
SMILES:
[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)NCCCn3cc(CC(C)(C)c4ocnc4\C=c4/[nH]c(=O)\c(=C\c5cccc(c5)C(=O)c5ccccc5)[nH]c4=O)nn3)[C@@]1([H])NC(=O)N2 |r|
Structure:
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