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Target
Solute carrier family 22 member 3
Ligand
BDBM55121
Substrate
n/a
Meas. Tech.
ChEMBL_839168 (CHEMBL2077839)
IC50
62000±n/a nM
Citation
 Wu, X; Kekuda, R; Huang, W; Fei, YJ; Leibach, FH; Chen, J; Conway, SJ; Ganapathy, V Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter (uptake2) and evidence for the expression of the transporter in the brain. J Biol Chem 273:32776-86 (1998) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 3
Synonyms:
Oct3 | Organic cation transporter 3 | S22A3_RAT | Slc22a3 | Solute carrier family 22 member 3
Type:
PROTEIN
Mol. Mass.:
61058.15
Organism:
Rattus norvegicus
Description:
ChEMBL_104125
Residue:
551
Sequence:
MPTFDQALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSPEEEWNLTTPELHVPAERRGQGHCHRYLLEDTNTSSELSCDPLAAFPNRSAPLVPCSGDWRYVETHSTIVSQFDLVCGNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIVYLISCFGVGITGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCFVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHLSSNYSEITVTDEEVSNPSCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIGGNLYMDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGILASVCGGLVMLLPETKGIALPETVEDVEKLGSSQLHQCGRKKKTQVSTSNV
  
Inhibitor
Name:
BDBM55121
Synonyms:
3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-aminoethyl)pyrocatechol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | Dopamine | MLS000069419 | SMR000059081 | cid_65340
Type:
Small organic molecule
Emp. Form.:
C8H11NO2
Mol. Mass.:
153.1784
SMILES:
NCCc1ccc(O)c(O)c1
Structure:
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