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Target
Monocarboxylate transporter 4
Ligand
BDBM50027176
Substrate
n/a
Meas. Tech.
ChEMBL_835931 (CHEMBL2077069)
IC50
970000±n/a nM
Citation
 Manning Fox, JE; Meredith, D; Halestrap, AP Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J Physiol (Lond) 529:285-93 (2000) [PubMed]  Article 
Target
Name:
Monocarboxylate transporter 4
Synonyms:
MCT 4 | MCT3 | MCT4 | MOT4_HUMAN | SLC16A3 | Solute carrier family 16 member 3
Type:
PROTEIN
Mol. Mass.:
49474.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104604
Residue:
465
Sequence:
MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
  
Inhibitor
Name:
BDBM50027176
Synonyms:
2-Acetoxy-Benzoic Acid | 3-Isobutyl-Methylxanthine | CHEBI:34795 | ISOBUTYLMETHYLXANTHINE
Type:
Small organic molecule
Emp. Form.:
C10H14N4O2
Mol. Mass.:
222.2438
SMILES:
CC(C)Cn1c2[nH]cnc2c(=O)n(C)c1=O
Structure:
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