Reaction Details Report a problem with these data
Target
Solute carrier organic anion transporter family member 1C1
Ligand
BDBM50375594
Substrate
n/a
Meas. Tech.
ChEMBL_838508 (CHEMBL2078136)
Ki
109000±n/a nM
Citation
 Tohyama, K; Kusuhara, H; Sugiyama, Y Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. Endocrinology 145:4384-91 (2004) [PubMed]  Article 
Target
Name:
Solute carrier organic anion transporter family member 1C1
Synonyms:
OATP-14 | OATP-F | OATP2 | Oatp1c1 | Oatpf | Organic anion transporter 2 | Organic anion transporter F | Organic anion-transporting polypeptide 14 | SO1C1_MOUSE | Slc21a14 | Slco1c1 | Solute carrier family 21 member 14 | Solute carrier organic anion transporter family member 1C1 | Thyroxine transporter
Type:
PROTEIN
Mol. Mass.:
78347.58
Organism:
Mus musculus
Description:
ChEMBL_104629
Residue:
715
Sequence:
MDTSSKENAHLFHKNSAQPAGGPSFTVGYPSTEEARPCCGKLKVFLGALSFVYFAKALAEGYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKSQNKISHECVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSRENSGSTSEKSKFIDDPIHYQMAPGDDKMKIMEMAKDFLPSLKTLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYVSACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSMAVLFVLKKKYVSKHSSLITTREKIGMSSSIKKETCAARDRGLQPKYWPGKETRL
  
Inhibitor
Name:
BDBM50375594
Synonyms:
TAUROCHOLATE
Type:
Small organic molecule
Emp. Form.:
C26H45NO7S
Mol. Mass.:
515.703
SMILES:
C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C |r|
Structure:
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