Reaction Details Report a problem with these data
Target
Solute carrier family 15 member 2
Ligand
BDBM50162073
Substrate
n/a
Meas. Tech.
ChEMBL_835999 (CHEMBL2077231)
Ki
390000±n/a nM
Citation
 Ganapathy, ME; Huang, W; Wang, H; Ganapathy, V; Leibach, FH Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2. Biochem Biophys Res Commun 246:470-5 (1998) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 2
Synonyms:
Oligopeptide transporter, kidney isoform | Pept2 | S15A2_RAT | Slc15a2
Type:
PROTEIN
Mol. Mass.:
81331.63
Organism:
Rattus norvegicus
Description:
ChEMBL_838253
Residue:
729
Sequence:
MNPFQKNESKETLFSPVSTEEMLPRPPSPPKKSPPKIFGSSYPVSIAFIVVNEFCERFSYYGMKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGKMLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEEEHAEARTRYFSVFYLAINAGSLISTFITPMLRGDVKCFGQDCYALAFGVPGLLMVLALVVFAMGSKMYRKPPPEGNIVAQVIKCIWFALCNRFRNRSGDLPKRQHWLDWAAEKYPKHLIADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLGFFVLQPDQMQVLNPFLVLIFIPLFDLVIYRLISKCRINFSSLRKMAVGMILACLAFAVAALVETKINGMIHPQPASQEIFLQVLNLADGDVKVTVLGSRNNSLLVESVSSFQNTTHYSKLHLEAKSQDLHFHLKYNSLSVHNDHSVEEKNCYQLLIHQDGESISSMLVKDTGIKPANGMAAIRFINTLHKDLNISLDTDAPLSVGKDYGVSAYRTVLRGKYPAVHCETEDKVFSLDLGQLDFGTTYLFVITNITSQGLQAWKAEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLVVAQFSGLAQWAEFVLFSCLLLVVCLIFSVMAYYYVPLKSEDTREATDKQIPAVQGNMINLETKNTRL
  
Inhibitor
Name:
BDBM50162073
Synonyms:
(S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)ethyl 2-amino-3-methylbutanoate | (S)-2-Amino-3-methyl-butyric acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester | CHEMBL1349 | VALACYCLOVIR
Type:
Small organic molecule
Emp. Form.:
C13H20N6O4
Mol. Mass.:
324.3357
SMILES:
CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O |r|
Structure:
Search PDB for entries with ligand similarity: