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Target
Muscarinic acetylcholine receptor DM1
Ligand
BDBM81901
Substrate
n/a
Meas. Tech.
ChEMBL_906756 (CHEMBL3051465)
Ki
4.8±n/a nM
Citation
 Honda, H; Tomizawa, M; Casida, JE Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. J Agric Food Chem 55:2276-81 (2007) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor DM1
Synonyms:
ACM1_DROME | AcrC | Muscarinic acetylcholine receptor DM1 | mAChR-A | mAcR-60C | mAcR-60C
Type:
PROTEIN
Mol. Mass.:
86647.10
Organism:
Drosophila melanogaster
Description:
ChEMBL_106611
Residue:
805
Sequence:
MEPVMSLALAAHGPPSILEPLFKTVTTSTTTTTTTTTSTTTTTASPAGYSPGYPGTTLLTALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWRRPRSESSPDAESVYMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDSDDFAYEQEEPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTPLPRPPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGLGTTGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQGDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQHDARLLNAKVIPKQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTCSDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTCKWHTRNREGMVRGVYN
  
Inhibitor
Name:
BDBM81901
Synonyms:
AF-DX 384 | CAS_119356 | CHEMBL279453 | NSC_119356
Type:
Small organic molecule
Emp. Form.:
C27H38N6O2
Mol. Mass.:
478.6296
SMILES:
CCCN(CCC)CC1CCCCN1CCNC(=O)N1c2ccccc2C(=O)Nc2cccnc12
Structure:
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