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Target
Muscarinic acetylcholine receptor DM1
Ligand
BDBM50240416
Substrate
n/a
Meas. Tech.
ChEMBL_906757 (CHEMBL3053219)
Ki
>100000±n/a nM
Citation
 Honda, H; Tomizawa, M; Casida, JE Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. J Agric Food Chem 55:2276-81 (2007) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor DM1
Synonyms:
ACM1_DROME | AcrC | Muscarinic acetylcholine receptor DM1 | mAChR-A | mAcR-60C | mAcR-60C
Type:
PROTEIN
Mol. Mass.:
86647.10
Organism:
Drosophila melanogaster
Description:
ChEMBL_106611
Residue:
805
Sequence:
MEPVMSLALAAHGPPSILEPLFKTVTTSTTTTTTTTTSTTTTTASPAGYSPGYPGTTLLTALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWRRPRSESSPDAESVYMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDSDDFAYEQEEPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTPLPRPPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGLGTTGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQGDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQHDARLLNAKVIPKQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTCSDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTCKWHTRNREGMVRGVYN
  
Inhibitor
Name:
BDBM50240416
Synonyms:
CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphate | diethyl 4-nitrophenyl phosphate | diethyl p-nitrophenyl phosphate | diethyl paraoxon | ethyl paraoxon | p-nitrophenyl diethyl phosphate | paraoxon | phosphacol | phosphoric acid diethyl 4-nitrophenyl ester
Type:
Small organic molecule
Emp. Form.:
C10H14NO6P
Mol. Mass.:
275.195
SMILES:
CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: