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Target
Muscarinic acetylcholine receptor DM1
Ligand
BDBM50229526
Substrate
n/a
Meas. Tech.
ChEMBL_906757 (CHEMBL3053219)
Ki
1330±n/a nM
Citation
 Honda, H; Tomizawa, M; Casida, JE Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists. J Agric Food Chem 55:2276-81 (2007) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor DM1
Synonyms:
ACM1_DROME | AcrC | Muscarinic acetylcholine receptor DM1 | mAChR-A | mAcR-60C | mAcR-60C
Type:
PROTEIN
Mol. Mass.:
86647.10
Organism:
Drosophila melanogaster
Description:
ChEMBL_106611
Residue:
805
Sequence:
MEPVMSLALAAHGPPSILEPLFKTVTTSTTTTTTTTTSTTTTTASPAGYSPGYPGTTLLTALFENLTSTAASGLYDPYSGMYGNQTNGTIGFETKGPRYSLASMVVMGFVAAILSTVTVAGNVMVMISFKIDKQLQTISNYFLFSLAIADFAIGAISMPLFAVTTILGYWPLGPIVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTNRAAVMIGAAWGISLLLWPPWIYSWPYIEGKRTVPKDECYIQFIETNQYITFGTALAAFYFPVTIMCFLYWRIWRETKKRQKDLPNLQAGKKDSSKRSNSSDENTVVNHASGGLLAFAQVGGNDHDTWRRPRSESSPDAESVYMTNMVIDSGYHGMHSRKSSIKSTNTIKKSYTCFGSIKEWCIAWWHSGREDSDDFAYEQEEPSDLGYATPVTIETPLQSSVSRCTSMNVMRDNYSMGGSVSGVRPPSILLSDVSPTPLPRPPLASISQLQEMSAVTASTTANVNTSGNGNGAINNNNNASHNGNGAVNGNGAGNGSGIGLGTTGNATHRDSRTLPVINRINSRSVSQDSVYTILIRLPSDGASSNAANGGGGGPGAGAAASASLSMQGDCAPSIKMIHEDGPTTTAAAAPLASAAATRRPLPSRDSEFSLPLGRRMSHAQHDARLLNAKVIPKQLGKAGGGAAGGGVGGAHALMNARNAAKKKKKSQEKRQESKAAKTLSAILLSFIITWTPYNILVLIKPLTTCSDCIPTELWDFFYALCYINSTINPMCYALCNATFRRTYVRILTCKWHTRNREGMVRGVYN
  
Inhibitor
Name:
BDBM50229526
Synonyms:
CHEMBL279356
Type:
Small organic molecule
Emp. Form.:
C10H15N3O
Mol. Mass.:
193.2456
SMILES:
Cc1noc(n1)C1CN2CCC1CC2 |(5.41,-5.22,;4.1,-6,;4.34,-7.52,;2.94,-8.22,;1.87,-7.15,;2.56,-5.75,;.54,-7.93,;.54,-9.47,;-.8,-10.25,;-2.11,-9.47,;-2.11,-7.93,;-.8,-7.16,;-1.21,-8.65,;-.19,-8.97,)|
Structure:
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