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Target
Pyrroline-5-carboxylate reductase
Ligand
BDBM50487061
Substrate
n/a
Meas. Tech.
ChEMBL_907087 (CHEMBL3067704)
Ki
199000±n/a nM
Citation
 Forlani, G; Giberti, S; Berlicki, L; Petrollino, D; Kafarski, P Plant P5C reductase as a new target for aminomethylenebisphosphonates. J Agric Food Chem 55:4340-7 (2007) [PubMed]  Article 
Target
Name:
Pyrroline-5-carboxylate reductase
Synonyms:
1.5.1.2 | EMB2772 | EMB2772 | P5C reductase | P5CR | P5CR1_ARATH | PROC1 | Protein EMBRYO DEFECTIVE 2772 | Pyrroline-5-carboxylate reductase
Type:
PROTEIN
Mol. Mass.:
28626.28
Organism:
Arabidopsis thaliana
Description:
ChEMBL_105520
Residue:
276
Sequence:
MEILPIPAESFKVGFIGAGKMAESIARGVVASGVLPPNRICTAVHSNLNRRDVFESFGVNVFSTSEEVVKESDVVIFSVKPQVVKKAVTELKSKLSKNKILVSVAAGIKLNDLQEWSGQDRFIRVMPNTPAAVGEAASVMSLGTGATEEDGAIVAMLFGAVGKILKADEKMFDAVTGLSGSGPAYIFLAIEALADGGVAAGLPRELALSLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGVHELEKGSFRATLMNAVVAAAKRSRELSQS
  
Inhibitor
Name:
BDBM50487061
Synonyms:
(3,5-Dichlorophenylamino)Methylenediphosphonic Acid
Type:
Small organic molecule
Emp. Form.:
C7H9Cl2NO6P2
Mol. Mass.:
336.003
SMILES:
OP(O)(=O)C(Nc1cc(Cl)cc(Cl)c1)P(O)(O)=O
Structure:
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