Reaction Details Report a problem with these data
Target
Neuronal acetylcholine receptor subunit alpha-4
Ligand
BDBM50078048
Substrate
n/a
Meas. Tech.
ChEMBL_908844 (CHEMBL3067866)
Ki
2.2±n/a nM
Citation
 Tomizawa, M; Casida, JE Unique neonicotinoid binding conformations conferring selective receptor interactions. J Agric Food Chem 59:2825-8 (2011) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit alpha-4
Synonyms:
ACHA4_CHICK | CHRNA4
Type:
PROTEIN
Mol. Mass.:
70849.36
Organism:
Gallus gallus
Description:
ChEMBL_492116
Residue:
622
Sequence:
MGFLVSKGNLLLLLCASIFPAFGHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPQEYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRIKWMPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLVSMHSHVDQLDYWESGEWVIINAVGNYNSKKYECCTEIYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSPRTHTMPDWVRRVFLDIVPRLLFMKRPSTVKDNCKKLIESMHKLTNSPRLWSETDMEPNFTTSSSPSPQSNEPSPTSSFCAHLEEPAKPMCKSPSGQYSMLHPEPPQVTCSSPKPSCHPLSDTQTTSISKGRSLSVQQMYSPNKTEEGSIRCRSRSIQYCYLQEDSSQTNGHSSASPASQRCHLNEEQPQHKPHQCKCKCRKGEAAGTPTQGSKSHSNKGEHLVLMSPALKLAVEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAGMI
  
Inhibitor
Name:
BDBM50078048
Synonyms:
1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-(2Z)-ylideneamine | 1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-2-ylidene-ammonium | 1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-2-ylideneamine | CHEMBL309804
Type:
Small organic molecule
Emp. Form.:
C9H11ClN4
Mol. Mass.:
210.663
SMILES:
NC1=NCCN1Cc1ccc(Cl)nc1 |t:1|
Structure:
Search PDB for entries with ligand similarity: