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Target
Cannabinoid receptor 1
Ligand
BDBM50537514
Substrate
n/a
Meas. Tech.
ChEMBL_1969936 (CHEMBL4602754)
EC50
7.0±n/a nM
Citation
 Zhao, C; Rakesh, KP; Ravidar, L; Fang, WY; Qin, HL Pharmaceutical and medicinal significance of sulfur (S Eur J Med Chem 162:679-734 (2019) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50537514
Synonyms:
CHEMBL4647333
Type:
Small organic molecule
Emp. Form.:
C19H28N4O3S
Mol. Mass.:
392.516
SMILES:
Cc1cc(no1)S(=O)(=O)N1CCc2c(C1)nc(CC(C)(C)C)n2CC1CC1
Structure:
Search PDB for entries with ligand similarity: