Reaction Details
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Phosphodiesterase
Ligand
BDBM50487543
Substrate
n/a
Meas. Tech.
ChEMBL_909521 (CHEMBL3055687)
IC50
2410000±n/a nM
Citation
TBA Med Chem Res 18:268-276 (2009) Article More Info.:
Target
Name:
Phosphodiesterase
Synonyms:
3.1.4.- | PDE7B | Phosphodiesterase
Type:
PROTEIN
Mol. Mass.:
50563.76
Organism:
Bos taurus
Description:
ChEMBL_106550
Residue:
438
Sequence:
MPVLERYFHSAELGRRWTAPEGELPAPLGSRPGCQQGPLPWDLPEMIRMVKLVWKSKSELQATKQRGILENEDALHSIPGDVRLRGQTGVPAERRGSYPFIDFRLLNNTTHSGEIGTKKKVKRLLSFQRYFHASRLLRGIIPQAPLHLLDEDYLGQARHMLSKVGMWDFDIFLFDRLTNGNSLVTLLCHLFNTHGLIHHFKLDMVTLHRFLVMVQEDYHSQNPYHNAVHAADVTQAMHCYLKEPKLASFLTPLDIMLGLLAAAAHDVDHPGVNQPFLIKTNHHLANLYQNMSVLENHHWRSTIGMLRESRLLAHLPKEMTQDIEQQLGSLILATDINRQNEFLTRLKAHLHNKDLRLEEVHDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGDLEQKFELEISPLCNQQKDSIPSIQIGELSSIVILNE
Inhibitor
Name:
BDBM50487543
Synonyms:
CHEMBL2262752
Type:
Small organic molecule
Emp. Form.:
C23H17N3OS
Mol. Mass.:
383.466
SMILES:
Cc1cc(C)c2nc(sc2c1)-n1c(nc2ccccc2c1=O)-c1ccccc1
Structure:
