Reaction Details Report a problem with these data
Target
Dipeptidyl peptidase 3
Ligand
BDBM50056999
Substrate
n/a
Meas. Tech.
ChEMBL_913306 (CHEMBL3062798)
Ki
70000±n/a nM
Citation
 Dhanda, S; Singh, J; Singh, H Goat brain enkephalin degrading enzyme: interaction with analgesic and antihypertensive drugs Med Chem Res 20:1294-7 (2011)    Article 
Target
Name:
Dipeptidyl peptidase 3
Synonyms:
3.4.14.4 | Dipeptidyl aminopeptidase III | Dipeptidyl peptidase 3 | Dipeptidyl peptidase III | M91_14005
Type:
PROTEIN
Mol. Mass.:
82027.05
Organism:
Bos mutus
Description:
ChEMBL_117383
Residue:
730
Sequence:
MADTQYILPNDIGVSSLDCREAFRLLSSTERLYAHYLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQICGELMFSLESRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVGQDGKPSYEVRLASVLGTEPNLDSEMNSKLKSYEFQGSHFRVTRGDYAPILQKVVEQLEKAKAYAANSHQEQMLAQYIESFTQGSIEAHKKGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAMVNKAMSAKFEWLVASAEQLLKELPWPPAFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEEDKDLYIRWKGPSFDVQVGLHELLGHGSGKLFMQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPRVLEIFGFEGADAEDVVYVNWLNMVRAGLLALEFYTPEASSWRQAHMQARFVILRVLLEAGEGLVTVTPTTGSDGRPDARVRLDRDKIRTVGKPALERFLRRLQVLKSTGDVAGGRALYEGYAAVTDAPPECFLSLRDTVLLRKEARKLIVQPNTRLEGSEVQLLEYEASAAGLIRSFSERFLEDGPELEKILTQLATADAQCWKGPQ
  
Inhibitor
Name:
BDBM50056999
Synonyms:
CHEMBL56367 | nimesulide
Type:
Small organic molecule
Emp. Form.:
C13H12N2O5S
Mol. Mass.:
308.31
SMILES:
CS(=O)(=O)Nc1ccc(cc1Oc1ccccc1)[N+]([O-])=O
Structure:
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