Reaction Details Report a problem with these data
Target
Ecdysone receptor/Ultraspiracle protein
Ligand
BDBM50178988
Substrate
n/a
Meas. Tech.
ChEMBL_927054 (CHEMBL3073225)
Ki
<501187±n/a nM
Citation
 Tohidi-Esfahani, D; Lawrence, MC; Graham, LD; Hannan, GN; Simpson, AM; Hill, RJ Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. Pest Manag Sci 67:1457-67 (2011) [PubMed]  Article 
Target
Name:
Ecdysone receptor/Ultraspiracle protein
Synonyms:
Ecdysone receptor
Type:
n/a
Mol. Mass.:
n/a
Description:
ASSAY_ID of ChEMBL is 927054
Components:
This complex has 2 components.
Component 1
Name:
Ecdysone receptor
Synonyms:
EcR | Ecdysone receptor
Type:
PROTEIN
Mol. Mass.:
34215.82
Organism:
Bemisia tabaci
Description:
ChEMBL_106721
Residue:
297
Sequence:
PECVVPEFQCAVKRKEKKAQKDKDKPNSTTSCSPDGIKQEIDPQRLDTDSQLLSVNGVKPITPEQEELIHRLVYFQNEYEHPSPEDIKRIVNAAPEEENVAEERFRHITEITILTVQLIVEFSKRLPGFDKLIREDQIALLKACSSEVMMFRMARRYDAETDSILFATNQPYTRESYTVAGMGDTVEDLLRFCRHMCAMKVDNAEYALLTAIVIFSERPSLSEGWKVEKIQEIYIEALKAYVENRRKPYATTIFAKLLSVLTELRTLGNMNSETCFSLKLKNRKVPSFLEEIWDVVS
  
Component 2
Name:
Ultraspiracle protein
Synonyms:
Ultraspiracle protein
Type:
PROTEIN
Mol. Mass.:
28672.51
Organism:
Bemisia tabaci
Description:
ChEMBL_106721
Residue:
251
Sequence:
KREAVQEERQRNKEKSENEVESTSNSQNDMPIERILEAELRVEPKNEDIDSRDPVSDICQAADRQLYQLIEWAKHIPHFTELPVEDQVILLKSGWNELLIAGFSHRSMSVKDGIMLATGLVVHRNCAHQAGVGAIFDRVLTELVAKMREMKMDKTELGCLRSIVLFNPEAKGLKSTQQVENLREKVYAILEEYCRQTYPDQSGRFAKLLLRLPALRSIGLKCLEHLFFFKLVGNTSIDSFLLSMLESNSDS
  
Inhibitor
Name:
BDBM50178988
Synonyms:
CHEBI:38452 | Tebufenozide
Type:
Small organic molecule
Emp. Form.:
C22H28N2O2
Mol. Mass.:
352.4699
SMILES:
CCc1ccc(cc1)C(=O)NN(C(=O)c1cc(C)cc(C)c1)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: