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Target
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic
Ligand
BDBM50488598
Substrate
n/a
Meas. Tech.
ChEMBL_925783 (CHEMBL3069076)
IC50
35±n/a nM
Citation
 Witschel, M; Röhl, F; Niggeweg, R; Newton, T In search of new herbicidal inhibitors of the non-mevalonate pathway. Pest Manag Sci 69:559-63 (2013) [PubMed]  Article 
Target
Name:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic
Synonyms:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase | AtMECT | AtMEPCT | ISPD | ISPD_ARATH | MCT | MECT | MEP cytidylyltransferase | MEPCT | MEPCT
Type:
PROTEIN
Mol. Mass.:
33935.84
Organism:
Arabidopsis thaliana
Description:
ChEMBL_105555
Residue:
302
Sequence:
MAMLQTNLGFITSPTFLCPKLKVKLNSYLWFSYRSQVQKLDFSKRVNRSYKRDALLLSIKCSSSTGFDNSNVVVKEKSVSVILLAGGQGKRMKMSMPKQYIPLLGQPIALYSFFTFSRMPEVKEIVVVCDPFFRDIFEEYEESIDVDLRFAIPGKERQDSVYSGLQEIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGAAVLGVPAKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPELLKKGFELVKSEGLEVTDDVSIVEYLKHPVYVSQGSYTNIKVTTPDDLLLAERILSEDS
  
Inhibitor
Name:
BDBM50488598
Synonyms:
CHEMBL2289489
Type:
Small organic molecule
Emp. Form.:
C14H9ClN4O
Mol. Mass.:
284.7
SMILES:
Oc1c(Cc2ccccc2)c(Cl)nc2c(cnn12)C#N
Structure:
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