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Target
RNA-directed RNA polymerase
Ligand
BDBM50191528
Substrate
n/a
Meas. Tech.
ChEMBL_932863 (CHEMBL3074361)
IC50
10209395±n/a nM
Citation
  TBA Med Chem Res 22:1866-1883 (2013)    Article 
Target
Name:
RNA-directed RNA polymerase
Synonyms:
2.7.7.48 | NS5B | RNA-directed RNA polymerase
Type:
PROTEIN
Mol. Mass.:
13231.83
Organism:
Hepatitis C virus genotype 1
Description:
ChEMBL_106647
Residue:
121
Sequence:
RCFDSTVTENDIRVEESIYQCCDLDPQARVAIKSLTERLYVGGPFTNSRGENCGYRRCRASGVLTTRCGNTLTCYMKAQAACRAARLRDCTMLVSGDDLVVICESAGAQEDAASLRAFTEA
  
Inhibitor
Name:
BDBM50191528
Synonyms:
2-[4-(4-chloro-4'-methylbiphenyl-2-ylmethoxy)phenyl]-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid | CHEMBL378546
Type:
Small organic molecule
Emp. Form.:
C34H31ClN2O3
Mol. Mass.:
551.075
SMILES:
Cc1ccc(cc1)-c1ccc(Cl)cc1COc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O
Structure:
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