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Target
D-alanine--D-alanine ligase
Ligand
BDBM7460
Substrate
n/a
Meas. Tech.
ChEMBL_931221 (CHEMBL3074976)
Ki
4300±n/a nM
Citation
  TBA Med Chem Res 22:2139-2150 (2013)    Article 
Target
Name:
D-alanine--D-alanine ligase
Synonyms:
6.3.2.4 | D-Ala-D-Ala ligase | D-alanine--D-alanine ligase | D-alanylalanine synthetase | DDL_HELPH | ddl
Type:
PROTEIN
Mol. Mass.:
39688.02
Organism:
Helicobacter pylori (strain HPAG1)
Description:
ChEMBL_106632
Residue:
347
Sequence:
MEFCVLFGGASFEHEISIVSAIALKGVLKDRIKYFIFLDENHHFYLIEASNMHSKYFAQIKEKKLPPLILTHKGLLKNSFLGAKIIELPLVINLVHGGDGEDGKLASLLEFYRIAFIGPRIEASVLSYNKYLTKLYAKDLGIKTLDHVLLNEKNRANAMDLINFNFPFIIKPNSAGSSLGVSVVKEEKELNYALDSAFEYSKEVLIEPFIQGVKEYNLAGCKIKKDFCFSYVEEPNKQEFLDFKQKYLDFSRTKAPKANLSNALEEQLKENFKKLYNDLFDGAIIRCDFFVIENEVYLNEINPIPGSLANYLFDDFKTTLENLAQSLPKTPKIQIKNSYLLQIQKNK
  
Inhibitor
Name:
BDBM7460
Synonyms:
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate | CHEMBL50 | Quercetin | Quercetin (10) | Quercetin (21) | Quercetin (Qur) | US11021454, Compound Quercetin | US9180183, Quercetin | med.21724, Compound 4
Type:
Small organic molecule
Emp. Form.:
C15H10O7
Mol. Mass.:
302.2357
SMILES:
Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Structure:
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