Reaction Details Report a problem with these data
Target
Tissue factor
Ligand
BDBM50488795
Substrate
n/a
Meas. Tech.
ChEMBL_932090 (CHEMBL3072496)
IC50
13±n/a nM
Citation
  TBA Med Chem Res 22:3242-3246 (2013)    Article 
Target
Name:
Tissue factor
Synonyms:
CD_antigen=CD142 | Coagulation factor III | Coagulation factor VII/tissue factor | F3 | TF | TF_HUMAN | Thromboplastin | Tissue factor
Type:
PROTEIN
Mol. Mass.:
33067.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_936735
Residue:
295
Sequence:
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
  
Inhibitor
Name:
BDBM50488795
Synonyms:
CHEMBL584437 | Go-Y013
Type:
Small organic molecule
Emp. Form.:
C19H18O3
Mol. Mass.:
294.3444
SMILES:
COc1ccc(\C=C\C(=O)\C=C\c2ccc(OC)cc2)cc1
Structure:
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