Reaction Details Report a problem with these data
Target
Tissue factor
Ligand
BDBM50067044
Substrate
n/a
Meas. Tech.
ChEMBL_932090 (CHEMBL3072496)
IC50
2.6±n/a nM
Citation
  TBA Med Chem Res 22:3242-3246 (2013)    Article 
Target
Name:
Tissue factor
Synonyms:
CD_antigen=CD142 | Coagulation factor III | Coagulation factor VII/tissue factor | F3 | TF | TF_HUMAN | Thromboplastin | Tissue factor
Type:
PROTEIN
Mol. Mass.:
33067.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_936735
Residue:
295
Sequence:
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
  
Inhibitor
Name:
BDBM50067044
Synonyms:
(1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-3-one | (1E,4E)-1,5-bis(4-hydroxyphenyl)penta-1,4-dien-3-one | 1,5-Bis(4-hydroxyphenyl)penta-1,4-dien-3-one | 1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-3-one | CHEMBL129134
Type:
Small organic molecule
Emp. Form.:
C17H14O3
Mol. Mass.:
266.2913
SMILES:
Oc1ccc(\C=C\C(=O)\C=C\c2ccc(O)cc2)cc1
Structure:
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