Reaction Details Report a problem with these data
Target
Protease
Ligand
BDBM151
Substrate
n/a
Meas. Tech.
ChEMBL_932804 (CHEMBL3072692)
Ki
0.300000±n/a nM
Citation
  TBA Med Chem Res 22:3918-3933 (2013)    Article 
Target
Name:
Protease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
10904.79
Organism:
Human immunodeficiency virus 1 (HIV-1)
Description:
Q9YQ12
Residue:
99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM151
Synonyms:
(4R,5S,6S,7R)-1,3-bis[(3-aminophenyl)methyl]-4,7-dibenzyl-5,6-dihydroxy-1,3-diazepan-2-one | CHEMBL223824 | DMP450
Type:
n/a
Emp. Form.:
C33H36N4O3
Mol. Mass.:
536.6639
SMILES:
Nc1cccc(CN2[C@H](Cc3ccccc3)[C@H](O)[C@@H](O)[C@@H](Cc3ccccc3)N(Cc3cccc(N)c3)C2=O)c1
Structure:
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