Reaction Details Report a problem with these data
Target
Cellular retinoic acid-binding protein 1
Ligand
BDBM50035477
Substrate
n/a
Meas. Tech.
ChEMBL_52395 (CHEMBL661351)
IC50
470±n/a nM
Citation
 Vaezi, MF; Alam, M; Sani, BP; Rogers, TS; Simpson-Herren, L; Wille, JJ; Hill, DL; Doran, TI; Brouillette, WJ; Muccio, DD A conformationally defined 6-s-trans-retinoic acid isomer: synthesis, chemopreventive activity, and toxicity. J Med Chem 37:4499-507 (1995) [PubMed]  Article 
Target
Name:
Cellular retinoic acid-binding protein 1
Synonyms:
CRABP1 | Cellular retinoic acid-binding protein I | RABP1_CHICK | cellular retinoic acid binding protein 1
Type:
PROTEIN
Mol. Mass.:
15660.02
Organism:
Gallus gallus
Description:
ChEMBL_52265
Residue:
137
Sequence:
MPNFAGTWKMRSSENFDELLKALGVNAMLRKVAVAAASKPHVEIRQDGDQFYIKTSTTVRTTEINFKIGESFEEETVDGRKCRSLATWENENKIYCKQTLIEGDGPKTYWTRELANDELILTFGADDVVCTRIYVRE
  
Inhibitor
Name:
BDBM50035477
Synonyms:
(2E,4E,6E)-8-[2-Isopropyl-3-methyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid | CHEMBL333032
Type:
Small organic molecule
Emp. Form.:
C20H28O2
Mol. Mass.:
300.4351
SMILES:
CC(C)C1=C(C)CCC\C1=C/C(/C)=C/C=C/C(/C)=C/C(O)=O |c:3|
Structure:
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